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#1 Children's Vitamin

~~Kid's vitamins should be healthy, shouldn't they? It that's the case they what's the case with the "Pediatricians' #1 Choice" namely  Flintstones Vitamins? They are manufactured by the global pharmaceutical corporation Bayer. This #1 seller has a shocking list of unhealthy ingredients, including:
• Aspartame
• Cupric Oxide
• Coal tar artificial coloring agents (FD&C Blue #2, Red #40, Yellow #6)
•  Zinc Oxide 
•  Sorbitol
• Ferrous Fumarate
•  Hydrogenated Oil (Soybean)
• GMO Corn starch
On Bayer Health Science's Flintstones product page designed for healthcare professionals they lead into the product description with the following tidbit of information:
 
"82% of kids aren't eating all of their veggies1. Without enough vegetables, kids may not be getting all of the nutrients they need." 
References:
1. Lorson BA, Melgar-Quinonez HR, Taylor CA. Correlates of fruit and vegetable intakes in US children. J Am Diet Assoc. 2009;109(3):474-478.
The implication here is that Flintstones vitamins somehow fill this nutritional void. But let's look a little closer at some of these presumably healthy ingredients....
 
 ASPARTAME 
 
Aspartame is a synthetic combination of the amino acids aspartic acid and l-phenylalanine, and is known to convert into highly toxic methanol and formaldehyde in the body.  Aspartame has been linked to over 40 adverse health effects in the biomedical literature, and has been shown to exhibit both neurotoxicity and carcinogenicity [1]  What business does a chemical like this have doing in a children's vitamin, especially when non-toxic, non-synthetic non-glycemic sweeteners like stevia already exist?
 
CUPRIC OXIDE 
 
Let's look closer at Cupric Oxide. 2mg of which is included in each serving of Flintstone's Complete chewable vitamins as a presumably  'nutritional' source of 'copper,' supplying "100% of the Daily Value  (Ages 4+), according to Flintstones Vitamins Web site's Nutritional Info.[2]
But what is Cupric Oxide? Is it a nutrient or a chemical?
According to the European Union's Dangerous Substance Directive, one of the main EU laws concerning chemical safety, Cupric Oxide is listed as a Hazardous substance, classified as
both "Harmful (XN)" and "Dangerous for the environment" (N).  Consider that it has industrial applications as a pigment in ceramics, and as a chemical in the production of rayon fabric and dry cell batteries. In may be technically correct to call it a mineral, but should it be listed as a nutrient in a children's vitamin? I for one don't think so.
 
COAL TAR ARTIFICIAL COLORING AGENTS 
 
One side effect of using synthetic dyes is aggravation attention-deficit hyperactivity disorder symptoms. For direct access to study abstracts on this topic view our Food Coloring research page.  There is also indication that the neurotoxicity of artificial food coloring agents increase when combined with aspartame,[3] making the combination of ingredients in Flintstones even more concerning.
 
ZINC OXIDE 
 
Each serving of Flintstones Complete Chewable vitamins contain 12 mg of zinc oxide, which the manufacturer claims delivers 75% of the Daily Value to children 2  & 3 years of age.  Widely used as a sun protection factor (SPF) in sunscreens, The EU's Dangerous Substance Directive classifies it as an environmental Hazard, "Dangerous for the environment (N)."  How it can be dangerous to the environment, but not for humans ingesting it, escapes me.  One thing is for sure, if one is to ingest supplemental zinc, or market it for use by children, it makes much more sense using a form that is organically bound (i.e. 'chelated') to an amino acid like glycine, as it will be more bioavailable and less toxic. This is the whole food form that I use here at the Center.
 
SORBITOL 
 
Sorbitol is a synthetic sugar substitute which is classified as a sugar alcohol. It can be argued that it has no place in the human diet, much less in a child's. The ingestion of higher amounts have been linked to gastrointestinal disturbances from abdominal pain to more serious conditions such as irritable bowel syndrome.[4]
  
FERROUS FUMARATE 
 
The one clear warning on the Flintstone's Web site concerns this chemical. While it is impossible to die from consuming iron from food, e.g. spinach, ferrous fumarate is an industrial mineral which is not found in nature in our food. In fact, ferrous fumarate is so toxic that accidental overdose of products containing this form is "a leading cause of fatal poisoning in children under 6." The manufacturer further warns: Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.
 
HYDROGENATED SOYBEAN OIL 
 
The use of hydrogenated oil in anything marketed to children is absolutely unacceptable. These semi-synthetic fatty acids are incorporate into our tissues and have been linked to over a dozen adverse health effects, from coronary artery disease to cancer, violent behavior to fatty liver disease.[5]
 
GMO CORN STARCH 
 
While it can be argued that the amount of GMO corn starch in this product is negligible, even irrelevant, I disagree. It is important to hold accountable those manufacturers that refuse to label their products honestly, especially when they contain ingredients that have been produced through genetic modification. The 'vitamin C' listed as ascorbic acid in Flintstones may also be produced from GMO corn. Let's remember that Bayer's Ag-biotech division, Bayer CropScience, poured $381,600 of cash into defeating the proposition 37 GMO labeling bill in California. I believe that parents have a right to protect their children against the well-known dangers of genetically modified foods and the agrichemicals that contaminate them. GMO corn starch is a "GMO PRODUCT" plain and simple, and should be labeled as such! We'd appreciate it if Bayer would label their "vitamins" accordingly.  
 
In summary, Bayer's Flintstone's vitamin brand is far from a natural product, and the consumer should be aware of the unintended, adverse health effects that may occur as a result of using it.
 
Resources 
[1] GreenMedInfo.com, Adverse Health Effects of Aspartame
[2] FlinstonesVitamins.com, FLINSTONES Complete Chewable
, Nutritional Info Overview 
[3] Karen Lau, W Graham McLean, Dominic P Williams, C Vyvyan Howard. Synergistic interactions between commonly used food additives in a developmental neurotoxicity test. Toxicol Sci. 2006 Mar;90(1):178-87. Epub 2005 Dec 13. PMID: 16352620
[4] GreenMedInfo.com, Sorbitol's Adverse Health Effects
[5] GreenMedInfo.com, Health Effects of Hydrogenated Oil
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